NetworkNewsBreaks – CytoDyn Inc. (CYDY) to Develop PRO 140 as Therapy for Triple-Negative Breast Cancer
Sep 5, 2018
Biotechnology company CytoDyn Inc. (OTCQB: CYDY) this morning detailed its plan to develop PRO 140 (leronlimab) as a therapy for metastatic triple-negative breast cancer. Per the update, previously announced findings from preclinical studies showed the ability of PRO 140 to block human breast cancer cellular invasion in a surrogate assay for metastatic breast cancer. “We plan to aggressively pursue the development of PRO 140 as a therapy for women with metastatic triple-negative breast cancer, which is in keeping with our strategy to evaluate PRO 140 in certain cancers and immunological indications where CCR5 antagonism has shown initial promise,” Nader Pourhassan, Ph.D., president and CEO of CytoDyn, stated in the news release. “In addition, we are continuing to move forward with plans to assess PRO 140 in metastatic colon cancer… We are pleased with our recent progress toward filing a Biologics License Application (BLA) for PRO 140 as a combination therapy for HIV and are confident that two thirds of our BLA submission will be completed by the end of 2018 and the last section, Chemistry, Manufacturing and Controls (CMC), by first quarter of 2019.”
To view the full press release, visit http://nnw.fm/qTJ4Q
About CytoDyn
CytoDyn is a biotechnology company focused on the clinical development and potential commercialization of humanized monoclonal antibodies for the treatment and prevention of HIV infection. The Company has one of the leading monoclonal antibodies under development for HIV infection, PRO 140, which has completed Phase 2 clinical trials with demonstrated antiviral activity in humans and is currently in Phase 3 development. PRO 140 blocks the HIV co-receptor CCR5 on T cells, which prevents viral entry. Clinical trial results thus far indicate that PRO 140 does not negatively affect the normal immune functions that are mediated by CCR5. Results from seven Phase 1 and Phase 2 human clinical trials have shown that PRO 140 can significantly reduce viral burden in people infected with HIV. A recent Phase 2b clinical trial demonstrated that PRO 140 can prevent viral escape in patients during several months of interruption from conventional drug therapy. CytoDyn intends to continue to develop PRO 140 as a therapeutic anti-viral agent in persons infected with HIV and to pursue non-HIV, inflammatory indications where CCR5 and its ligand CCL5 may be involved. For more information, visit the company’s website at www.CytoDyn.com
More from NetworkNewsBreaks
NetworkNewsBreaks – PreveCeutical Medical Inc. (CSE: PREV) (OTCQB: PRVCF) (FSE: 18H) Develops Proprietary Cannabinoid Extraction Protocol NetworkNewsBreaks – The Flowr Corp. Announces Close of C$36M Offering NetworkNewsBreaks – Earth Science Tech, Inc. (ETST) Reaches Fully Reporting Status with the SECAbout NetworkNewsWire
NetworkNewsWire (NNW) is an information service that provides (1) access to our news aggregation and syndication servers, (2) NetworkNewsBreaks that summarize corporate news and information, (3) enhanced press release services, (4) social media distribution and optimization services, and (5) a full array of corporate communication solutions. As a multifaceted financial news and content distribution company with an extensive team of contributing journalists and writers, NNW is uniquely positioned to best serve private and public companies that desire to reach a wide audience of investors, consumers, journalists and the general public. NNW has an ever-growing distribution network of more than 5,000 key syndication outlets across the country. By cutting through the overload of information in today’s market, NNW brings its clients unparalleled visibility, recognition and brand awareness. NNW is where news, content and information converge.
For more information please visit https://www.NetworkNewsWire.com
Please see full terms of use and disclaimers on the NetworkNewsWire website applicable to all content provided by NNW, wherever published or re-published: http://NNW.fm/Disclaimer
NetworkNewsWire (NNW)
New York, New York
www.NetworkNewsWire.com
212.418.1217 Office
[email protected]
NetworkNewsWire has received compensation from CytoDyn Inc. for providing certain investor relations, marketing and social media services, including the preparation of this report, and expects to receive additional compensation for such services in the future. This compensation includes a monthly program fee.
More News
P21,500 settlement ‘cut’ lands ex-fiscal in jail
MANILA, Philippines — The Sandiganbayan Fifth Division has found a former Taguig City senior assistant prosecutor guilty of three counts of violating the code of conduct and ethical standards for government workers after he took P21,500 as his “share” of the settlement in a homicide case in 2014. In a decision handed down on Oct.
_2026_10_15_08_00_30.jpg)
NBI issues subpoenas to 'Machong Chismisan' podcast members
The National Bureau of Investigation (NBI) has issued subpoenas to members of the "Machong Chismisan" podcast following their remarks about Joshua "Josh" Aquino, the son of Kris Aquino.
Before ‘maleta,’ durabox used to haul ‘kickbacks,’ court told
MANILA, Philippines — Before they started using suitcases (“maleta”), the alleged bagmen working for then Ako Bicol Rep. Zaldy Co used plastic bins to deliver millions of pesos in cash to various recipients as part of their share from public works kickbacks, a witness told the antigraft court on Thursday. In support of Rodante Orbillo’s
FACT CHECK: Viral photos of fire, ambulance trikes are AI-generated
The Patient Transport Vehicles distributed by Marcos were part of a program by the Philippine Charity Sweepstakes Office, but they do not resemble the tricycle-type 'Hospital on Wheels' shown in the viral post
SC rolls out e-notarization Oct. 19
MANILA, Philippines — The Supreme Court will begin rolling out digital notarization on Oct. 19, allowing accredited notaries to provide services regardless of their physical location and easing public access to legal services. The launch of electronic notarization, or e-notarization, marks a shift from traditional notarial services, which are restricted to a notary public’s territorial
‘Macho’ hosts turn meek, apologize for mocking Kris Aquino son Josh
MANILA, Philippines — What began as macho posturing on a podcast ended in profuse apologies after its all-male hosts faced fierce backlash for mocking celebrity Kris Aquino’s son, who is on the autism spectrum. Government agencies, advocates, and netizens came together on Thursday to criticize the podcast “Machong Chismisan” over its Oct. 5 episode, where
Senators: PH won't back down despite Chinese envoy's 'threats'
Several senators on Friday strongly denounced the supposed threats of Chinese Ambassador Jing Quan that Beijing could “easily win” against the Philippines if it resorted to force.
‘Dine in the dark’ puts disability employment into sharp focus
The Westin Manila’s Dine in the Dark is a win-win situation for visually impaired employees and hungry guests alike
6 firms in ‘onion cartel’ face P1.76-B fines, raps
MANILA, Philippines —After years of investigation, the Philippine Competition Commission (PCC) has imposed a record P1.76 billion in fines on six businesses and their officers for operating an onion cartel that was uncovered after onion prices surged to as much as P800 per kilogram in late 2022. At a press conference on Thursday, the antitrust
/file/attachments/orphans/IsmailBinLasim2_876768.jpg)
Duress, delay, then endorsement: N Sembilan MB must answer for role in royal crisis - Bar
Bar chief questions police report, support for royal removal, and exco decisions.
PNP: No politics involved in Laos-PH drug smuggling probe
The Philippine National Police (PNP) on Friday maintained that there's "no politics" in its ongoing probe on the attempt to smuggle P3.5 billion worth of illegal drugs from Laos to the Philippines.
Water shortage grips Northern Samar capital as El Niño strengthens
TACLOBAN CITY, LEYTE, Philippines — At least 31 of 55 barangays in Catarman, Northern Samar, are already experiencing reduced water supply as the local government prepares for worsening dry conditions brought by the El Niño phenomenon. This prompted local officials to explore additional water sources and urge residents to conserve water. The Catarman Water District
YOUR NEWS, OUR NETWORK.
Do you have Great News you want to tell the world?
Be it updates about your business or your community, you can make sure that it’s heard by submitting your story to our network reaching hundreds of news sites across 6 verticals.